The YMCA is planning to build a four-storey £8 million building with 71 units in Grimsby.
If plans are approved it will be developed at the former House of Holland Store on Freeman Street.
Plans include a cafe for training and work opportunities, a wellbeing space, as well as conference, exhibition and performance rooms.
They also plan to build a chapel for people to practise their different faiths when it opens.
More than 50 people will be employed at the new development after transferring from the current site in Peaks Lane.
Alongside this building on Freeman Street, architects are also drawing up plans for 16 town houses and a further 72 one and two-bed flats.
YMCA Humber Chief Executive Debbie Cook said: “YMCA Humber has a proud history, with a Christian ethos embedded in all we stand for.
“This ambitious plan is about the YMCA stepping us as a community leader to provide aspirational accommodation and opportunity for our residents and the local community.
“Basing ourselves in the heart of this community, where our support is needed, is really important to us.
“We will be able to work alongside partners and other groups to offer people, who need our help, true opportunity.”
The YMCA’s other 26-bed facility on the other side of Riby Square will remain open under the plans.