Police have closed the road on the A16 High Ferry in Sibsey after a crash on Tuesday afternoon.
The crash involved two vehicles.
Diversions are being put in place as there are delays in both directions between B1184 Frith Ville Road junction to the Pillies Lane junction.
Reporters tried to contact Lincolnshire Police for further information regarding injuries, as well as how long the road is expected to be closed for, but there was no reply by the time of publication.
Anyone with information about the crash should contact police on 101 quoting 310 of December 4.