Two men have been killed and four have been seriously injured in a fatal crash on the A1077 between South Ferriby and Barton.
The crash between a Vauxhall Astra and Audi TT happened at around 10.30pm on Friday, October 27.
Two men travelling in the Astra died.
Another man suffered potentially life-threatening injuries.
A further two sustained serious injuries not thought to be life-threatening.
The Audi driver, a 23-year-old man, suffered serious but not life-threatening injuries.
Police have not formally identified the two men killed.
The road was closed until 7.50am this morning to allow the emergency services to carry out their work.
Anyone who saw the crash should call Humberside Police on 101, quoting log 679 of October 27.