Drivers are being warned of severe delays on the A160 this rush hour after a lorry overturned.
The incident happened just after 3pm this afternoon on a stretch of the road between the A180 and A1077 near South Killingholme.
Emergency services, including the Lincolnshire and Nottinghamshire Air Ambulance, are at the scene.
It is not yet known at the time of writing how serious any injuries are.
Motorists are also being reminded that Humber Bridge will be closed to high sided vehicles from 11.30pm on Tuesday, September 12 to 6am on Wednesday, September 13.