A man and woman are in hospital with serious injuries after a crash involving a car and a lorry on the A15 near Waddingham.
As previously reported, the lorry, which was carrying 36 bales of straw, has overturned.
Police say a quantity of diesel has been spilled on the road and there is a 20m long gouge in the surface of the road, which requires repair works.
A car was also involved in the incident and the injured man and woman have been taken to Scunthorpe hospital.
The road is expected to remain closed until this evening.