The A46 southbound near Newark is closed after two lorries crashed.
Emergency services were called to the crash near Syerston which happened at around midday on Thursday, March 23.
One lorry shed its load and highways are currently dealing with a fuel spillage.
Police have said that the injuries are not life-threatening or life-altering.
One man is in hospital as a precaution.
The northbound carriageway is unaffected.
The road is expected to be closed into the evening.